GIBio TIM-1

TIM-1 is a dynamic, multi-compartment in vitro gastrointestinal model that simulates the physiological conditions of the human upper digestive tract, including the stomach, duodenum, jejunum, and ileum. The system reproduces key digestive processes such as gradual gastric emptying, changing pH, enzyme and bile secretion, peristaltic mixing, and intestinal transit over time.

TIM-1 is widely used to study oral drug and nutrient digestion, dissolution, and bioaccessibility under controlled laboratory conditions, providing a reproducible, non-animal method for predicting how compounds behave in the human gastrointestinal tract.